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The Download: “reprogramming” aging, and the hidden sense of interoception

This is today’s edition of The Download, our weekday newsletter that provides a daily dose of what’s going on in the world of technology. Why “reprogramming” is the buzziest approach to reversing aging right now Earlier this week, Life Biosciences, a biotech company focused on reversing age-related diseases, announced that it had dosed its first…
You do your own time

There we were, a regular murderers’ row of librarians. Little Jo. Eustace. And me. Turning around in the nave of our library to greet the sound of footsteps, pistols leveled in case whoever was coming in didn’t respect sanctuary. Little Jo had a stack of books under one arm. Eustace was holding the screwdriver she’d…
Why “reprogramming” is the buzziest approach to reversing aging right now

Earlier this week, Life Biosciences, a biotech company focused on reversing age-related diseases, announced that it had dosed its first volunteer. A person with glaucoma has had an experimental treatment injected straight into their eyeball. The idea is to try to treat the disease—which can cause vision loss—by regenerating healthy nerves in the eye. But…
Inside interoception: The hidden sense of how you feel inside

MIT Technology Review Explains: Let our writers untangle the complex, messy world of science and technology to help you understand what’s coming next. You can read more from the series here. Your brain lives in the dark space of your skull. Yet it knows when the wind lifts the hairs on your skin, when your heart is…
The Download: soccer’s data renaissance and China’s big nuclear plans

This is today’s edition of The Download, our weekday newsletter that provides a daily dose of what’s going on in the world of technology. Inside soccer’s data renaissance Imagine tuning in to the opening kickoff of a World Cup match and seeing a player intentionally kick the ball out of bounds. You may question the…
Google DeepMind is worried about what happens when millions of agents start to interact

Google DeepMind is funding research into the potential dangers of situations where millions of different AI agents interact with each other online. According to Rohin Shah, who directs the company’s AGI safety and alignment research, the mass-market arrival of agents that can carry out tasks without human oversight and follow instructions given to them by other…
Job titles of the future: Nature’s drug designer

In 2018, after nearly two decades working in Big Pharma, chemist Tim Cernak was ready to put his skills to a new use. For Merck, he’d developed precision therapies for cancer, HIV, and diabetes that could target disease while minimizing harm to healthy cells. But as a lifelong nature lover, he was increasingly concerned about…
Inside soccer’s data renaissance

Imagine tuning in to the opening kickoff of a World Cup match and seeing a player intentionally send the ball all the way down the pitch and right out of bounds on the opponent’s end. Casual fans might scratch their heads. Where’s the logic in surrendering possession seconds into a game? If you were Jesse…
Why China is betting on big nuclear reactors

It’s a tale of two nuclear industries. In China, large reactors are coming together at a stunning pace. The country has nearly doubled its nuclear fleet since 2016, reaching nearly 60 gigawatts of total power capacity. The new facilities are nearly all gigawatt-scale pressurized-water reactors. Meanwhile, the US has built just two reactors in that…
The Download: the “steroid olympics” and a safer Mythos

This is today’s edition of The Download, our weekday newsletter that provides a daily dose of what’s going on in the world of technology. The “steroid olympics” were a circus—and a window into our culture —Amit Katwala A couple of weeks ago, at a $50 million arena built in a casino parking lot in Las…